Tracy Reiner (Betty Spaghetti) & Janice from The Sopranos
Lo and behold, Betty Spaghetti was not played by Tony Soprano's sister! Doesn't it seem like she was, though? Betty Spaghetti was actually played by Tracy Reiner, who is Penny Marshall's daughter and Rob Reiner's step-daughter. Janice Baccalieri nee Soprano was played by Aida Turturro, who is cousins with John (at least according to Wikipedia). These are not the same actress. I'm positive.